Activities in Various Parts of the Nephron

    Bowman's capsuleFiltration of blood
    Proximal tubuleReabsorption (active transport) of glucose, amino acids, Ca2+, other electrolytes. Secretion of H+, K+, NH3, creatine, organic acids.
    Descending loopDiffusion of water and electrolytes
    Ascending loopActive reabsorption of Cl- (Na+ follows passively). Counter-current sytem establishes high osmotic pressure in medulla.
    Distal tubuleActive reabsorption of Na+ (Cl- follows passively). Secretion of H+, K+, NH3.
    Collecting ductreabsoption of water by osmosis (ADH-dependent). Secretion of H+, K+, NH3.

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